منابع مشابه
Essential hypertension and aldosterone.
MANY FACTORS have been implicated in the etiology of essential hypertension and at present the primary cause of this disease remains obscure. The relationship of sodium to the development of hypertension and the question of involvement of the adrenal cortex has been the subject of numerous investigations. Efforts by earlier investigators to show a hypersecretion of corticosteroids in this condi...
متن کاملRenin and aldosterone in essential hypertension.
1. The renin-aldosterone system was studied in seventy-one selected hypertensive patients. Nine (13%) were diagnosed as having primary aldosteronism. Ofthe twentythree patients who presented with a history of unprovoked hypokalaemia, the incidence of primary aldosteronism was 40%. 2. Renin and aldosterone responses to the combined stimuli of a low sodium diet and the upright posture were suppre...
متن کاملArterial pressure, left ventricular mass, and aldosterone in essential hypertension.
The purpose of the present study was to evaluate the relationship of aldosterone to blood pressure and left ventricular size in black American (n=109) and white French Canadian (n=73) patients with essential hypertension. Measurements were obtained with patients off antihypertensive medications and included 24-hour blood pressure monitoring, plasma renin activity and aldosterone, and an echocar...
متن کاملAldosterone is produced from ventricles in patients with essential hypertension.
This study was designed to examine whether aldosterone is produced from the hearts of patients with essential hypertension without left ventricular systolic dysfunction (LVSD). The study population consisted of 20 patients with essential hypertension without LVSD and 22 control subjects. Plasma levels of aldosterone, serum ACE activity, and B-type natriuretic peptide levels were measured in the...
متن کاملAldosterone antagonist improves diastolic function in essential hypertension.
Experimental studies demonstrated that mineralocorticoid antagonists prevent or reverse myocardial fibrosis. Therefore, we tested the hypothesis that the aldosterone antagonist canrenone can improve left ventricular diastolic function in essential hypertension. Using digitized M-mode echocardiography and 24-hour blood pressure monitoring (ABPM), we realized a prospective, randomized, controlled...
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ژورنال
عنوان ژورنال: Circulation
سال: 1961
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.23.2.168